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Anti-ETFB Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-ETFB Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-ETFB Antibody See all ETFB primary antibodies
Description:	Rabbit polyclonal antibody to ETFB
Specificity:	The antibody detects endogenous levels of total ETFB protein.
Applications:	IHC, WB
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide of human ETFB
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification
Concentration:	0.4mg / ml
Formulation:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage:	Store at -20?C

Target

Function:	The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
Tissue Specificity:	Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.
Involvement in Disease:	Glutaric aciduria 2B: An autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.
Sequence Similarities:	Belongs to the ETF beta-subunit/FixA family.
Post-Translational Modification:	Methylated. Trimethylation at Lys-200 and Lys-203 may negatively regulate the activity in electron transfer from Acyl-CoA dehydrogenases.
Cellular Location:	Mitochondrion matrix.
Database Links:	Entrez Gene: 2109?Human Entrez Gene: 110826?Mouse Omim: 130410?Human SwissProt: P38117?Human SwissProt: Q9DCW4?Mouse Unigene: 348531?Human Unigene: 30200?Mouse
Synonyms:	Beta ETF Antibody Beta-ETF Antibody Electron transfer flavoprotein beta polypeptide Antibody Electron transfer flavoprotein beta subunit Antibody Electron transfer flavoprotein subunit beta Antibody Electron transferring flavoprotein beta polypeptide Antibody ETFB Antibody ETFB_HUMAN Antibody FP585 Antibody MADD Antibody
Information:	Target information shown above is from the UniProt Consortium.