Synthetic peptide corresponding to Human FANCF (C terminal).
Sequence:
C-RQVLGLSAGLSSV
Host:
Goat
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Unconjugated
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:
100 μg at 0.5 mg/ml.
Product Form:
Liquid
Formulation:
Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Target
Function:
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability (By similarity).
Involvement in Disease:
Fanconi anemia complementation group F: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
Cellular Location:
Nucleus.
Database Links:
Entrez Gene: 2188?Human
Omim: 603467?Human
SwissProt: Q9NPI8?Human
Unigene: 713574?Human
Synonyms:
A730016A17 Antibody
FACF Antibody
FAF Antibody
FANCF Antibody
FANCF_HUMAN Antibody
Fanconi anemia complementation group F Antibody
Fanconi anemia group F protein Antibody
MGC126856 Antibody
Protein FACF Antibody
RGD1561456 Antibody
Information:
Target information shown above is from the UniProt Consortium.